Xiaobing WU

WU XIAOBING
PhD Fellow

Education:
Master of Medicine, Anhui Medical University, 2013 – 2016
Bachelor of Medicine, Anhui Medical University, 2008 – 2013

Work experience:
Physician, First People’s hospital of Hefei, 2016－2017

Publications:

1. Wu X, Guo M, Cui J, Cai H, Wang SM. Heterozygotic Brca1 mutation initiates mouse genome instability at embryonic stage. Oncogenesis. 2022 Jul 22;11(1):41. doi: 10.1038/s41389-022- 00417-3. PMID: 35869059; PMCID: PMC9307611.

2. Zhang L, Qin Z, Huang T, Tam B, Ruan Y, Guo M, Wu X, Li J, Zhao B, Chian JS, Wang X, Wang L, Wang SM. Prevalence and spectrum of DNA mismatch repair gene variation in the general Chinese population. J Med Genet. 2022 Jul;59(7):652-661. doi: 10.1136/jmedgenet2021-107886. Epub 2021 Jun 25. PMID: 34172528.

3. Zhang L, Bhaskaran SP, Huang T, Dong H, Chandratre K, Wu X, Qin Z, Wang X, Cao W, Chen T, Lynch H, Wang SM. Variants of DNA mismatch repair genes derived from 33,998 Chinese individuals with and without cancer reveal their highly ethnic-specific nature. Eur J Cancer. 2020 Jan;125:12-21. doi: 10.1016/j.ejca.2019.11.004. Epub 2019 Dec 9. PMID: 31830689.

4. Gupta H, Chandratre K, Sinha S, Huang T, Wu X, Cui J, Zhang MQ, Wang SM. Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition. BMC Genomics. 2020 Nov 30;21(1):842. doi: 10.1186/s12864-020- 07222-5. PMID: 33256598; PMCID: PMC7706239.

5. Bhaskaran SP, Chandratre K, Gupta H, Zhang L, Wang X, Cui J, Kim YC, Sinha S, Jiang L, Lu B, Wu X, Qin Z, Huang T, Wang SM. Germline variation in BRCA1/2 is highly ethnicspecific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients. Int J Cancer. 2019 Aug 15;145(4):962-973. doi: 10.1002/ijc.32176. Epub 2019 Feb 13. PMID: 30702160; PMCID: PMC6617753.

6. Wu XB, Liu Y, Wang GH, Xu X, Cai Y, Wang HY, Li YQ, Meng HF, Dai F, Jin JD. Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTORmediated NF-κB activation. Sci Rep. 2016 Feb 19;6:21420. doi: 10.1038/srep21420. PMID: 26892992; PMCID: PMC4759824.

7. Wang GH, Liu Y, Wu XB, Lu Y, Liu J, Qin YR, Li T, Duan HF. Neuroprotective effects of human umbilical cord-derived mesenchymal stromal cells combined with nimod

8. Liu Y, Li YQ, Wang HY, Wu XB, Jing YG, Xu X, YAO Y, Zhang Y, Wu CT, Jin JD. A new method to isolate mesenchymal stem cells from human placenta. Chinese Journal of Tissue Engineering Research. 2015;19(10):1608.

9. Liu Y, Wu X, Jing YG, Li YQ, Wang HY, Xu X, Wu CT, Jin JD. Establishment of an aging model of mesenchymal stem cells. Military Medical Sciences. 2015(5):329-33.

10. Li Y, Xu X, Wang L, Liu G, Li Y, Wu X, Jing Y, Li H, Wang G. Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression. Cell Biosci. 2015 May 6;5:21. doi: 10.1186/s13578-015-0012-3. PMID: 26273429; PMCID: PMC4535282.

11. Liu Y, Li YQ, Wang HY, Li YJ, Liu GY, Xu X, Wu XB, Jing YG, Yao Y, Wu CT, Jin JD. Effect of serum choice on replicative senescence in mesenchymal stromal cells. Cytotherapy. 2015 Jul;17(7):874-84. doi: 10.1016/j.jcyt.2015.02.012. Epub 2015 Mar 19. PMID: 25800776.

Contact Details:
Ph：+853-88224217
Email:yb77627@umac.mo

Current Affiliation:
The First Affiliated Hospital of Anhui Medical University, https://www.ayfy.com/